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Aspirin and Fertility


In This Article:
Aspirin and Fertility
Aspirin and Heparin Therapy
Aspirin and Fertility in the Long Term


AspirinAspirin is a widely used over-the-counter analgesic the anticoagulative properties (preventing blood from clotting) of which may offer benefits in the field of reproductive endocrinology.



Antiphospholipid Antibodies

Antiphospholipid antibodies (APA) are a class of proteins researchers believe to be related to problems of coagulation. Consequently, when clotting problems develop in the placenta and disrupt blood flow, it can lead to recurrent spontaneous abortion (more than two pregnancy losses) if the woman has elevated levels of these antibodies (detected through a series of blood tests). Aspirin therapy can significantly reduce this risk due to its anticoagulative properties. Often it is administered with heparin, another anticoagulant that works at a different phase of the process of coagulation.

The issue under research currently is whether this low-dose aspirin regimen in the management of APA-related disorders can also contribute to other aspects of the reproductive process, namely if aspirin can increase the blood supply to the uterus and ovaries. If so, it would mean that the uterus and ovaries would be on the receiving end of a more substantial dosage of serum-carried hormones, improving ovary productivity and thickening the lining of the uterus.

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