Multiple Miscarriages & Future Prognosis

Hi there, I am 32 years old

Hi there,

I am 32 years old and my husband is 34. We started trying for a baby since July 2008. Last year I had two miscarriages around 6-7 weeks. Both ended natually. After the second miscarriage we decided to get a full work up and everything came back normal including Karyotype, FSH (5.9/6.8), AFC count was 20, autoimmune and blood clotthing. My husband aslo had sperm DNA test done and it was excellent.
Our doc suggested we try a low dose of fertility meds(puregon) and we got pregnant on our first try with timed intercourse. Everything was perfect untill at at the 12 week U/S we found out the baby had T21 along with a large cystic hygoma. The progonsis was very poor and we decided for D&E.

We are absolutley heartbroken and wonder if there is hope for us in the future? Could this really be just bad luck or is there something wrong with my eggs?
What would your suggestions be for trying next time?

Thank-you so much for your input during this very dark time.

Dori, Please accept my

Please accept my sympathy for your losses. What a heartbreaking journey you have had. Trisomy 21 is a chromosomal abnormality that occues in women your age about 1 in 388 pregnancies.

I would make an appointment with a genetic counselor to fully explore any other testing that might be helpful for you to have and to help you evaluate your risks for future pregnancies.

To find one near you, go to:, the website for the National Society of Genetic Counselors.

Armed with that information, you can make a more informed decision about persuing third party reproduction.

Best, Angie


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