I am a 41 year old female. I have a 9 year old daughter. I have never had miscarriages but I have been told I have 46,XX,9qh+ cariotipe. I have tried a new pregnancy for three years now. Can this cariotipe the reason of my infertility? Doctors recomend me

Most (but not all) species

Most (but not all) species have a standard karyotype. The normal human karyotypes contain 22 pairs of autosomal chromosomes and one pair of sex chromosomes. Normal karyotypes for females contain two X chromosomes and are denoted 46,XX; males have both an X and a Y chromosome denoted 46,XY. Any variation from the standard karyotype may lead to developmental abnormalities.

So the 46,XX is normal. The 9qh+most probably represents a duplication of the heterochromatic secondary constriction in chromosome No. 9. Research indicates that such duplications might give an increased risk of chromosome abnormalities. For a better understanding of the karotypes and what this means for you, make an appointment with a genetic counselor.

At 41, make an appointment as soon as possible so you can determine the best course of action.



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