I've had three miscarriages and the last showed a large blood clot outside the pregnancy sac at 10 weeks. I never get ill - even if everyone aorund me has colds and coughs, I'm always fine. Do you think it's possible I have an overactive immune system?


Same thing happened to me. I

Same thing happened to me. I went to reproductive endocrinologist to find out what the deal is. He said a blood clot can be because of a clotting disorder. I had several simple blood test and am waiting the results. What he did find thus far was a septated uterus, on a test called SHG. This can be the reason for nonimplantation, miscarriage or just not making it to full term. I got the septate repaired surgically during a histroscope. They go in through the vagina. Although for some septated uterous they have to go in through the belly button. Mine was not that kind. Good luck and keep a positive attitude.

Up to a third of miscarriages

Up to a third of miscarriages are caused by an overactive immune system, so it is a possibility. Everyone has circulating in their body something called natural killer (NK) cells. They secrete a substance called TNF (tumor necrosis factor) and the overactivity of these cells producing their TNF - can be deadly to a pregnancy. Some women have over-active immune systems, causing the body to reject the implanted embryo. A possible treatment is called IVIG - intravenous immunoglobulin - and involves transfusions of blood products containing antibodies which suppress the faulty immune system. The drug is called Gammamune and it is administered through an IV over a period of three days each month (preconception). The treatment is controversial, with some experts still regarding it as experimental. A new clinical study shows that a steroid treatment may be beneficial for women suffering from multiple miscarriages. In the preliminary trials of the steroid - Prednisolone, 30 of the 40 women suffering from repeated miscarriages, all with high NK levels, went on to have successful pregnancies. So, talk to a fertility specialist about potential treatments before getting pregnant again. Best wishes, Angie

 
disclaimer

The information provided on ConceivingConcepts.com is designed to support, not replace, the relationship that exists between a patient/site visitor and his/her health professional. This information is solely for informational and educational purposes. The publication of this information does not constitute the practice of medicine, and this information does not replace the advice of your physician or other health care provider. Neither the owners or employees of ConceivingConcepts.com nor the author(s) of site content take responsibility for any possible consequences from any treatment, procedure, exercise, dietary modification, action or application of medication which results from reading this site. Always speak with your primary health care provider before engaging in any form of self treatment. See our Legal Statement for more details.

Fertility Clinics Directory

Find a Fertility Clinic

If you or a loved one is suffering from infertility and needs help conceiving then we are here to offer help in any way we can. We have over 450 Fertility Clinics listed on our Directory. Click here to search for a Fertility Clinic that is right for you.

babymaker