Endometrial scratching may increases chance of conception


It sounds terrible and it may in fact be painful, but a procedure known as endometrial scratching has been shown to improve both pregnant and birth rates when it is performed once in women who are undergoing reproductive treatment. “Early results are encouraging,” said Dr. Nick Raine-Fenning, of the Nottingham University Research and Treatment Unit (NURTURE).

Use during specific time frame increases odds of pregnancy

Endometrial scratching is medically assisted damage to the uterus first shown to be beneficial in 2003. The results of the procedure had not been fully studied or documented. Dr. Raine-Fenning and a team of Brazilian scientists found that specific timing of the endometrial scratching technique showed significant benefit toward achieving pregnancy. The researchers investigated the effect of endometrial scratching within a time frame of 7 to 14 days before core reproductive treatment began.

20% increased pregnancy rate

Of the 77 women who received the endometrial scratching, 39 became pregnant and 33 of those achieved live birth. The control group experienced 23 live births. The difference represents a 20% increased clinical pregnancy rate. The technique did not affect miscarriage or multiple pregnancy rates.

Results of trial are promising

“This is the first well-designed trial conducted into endometrial scratching and the results are promising. Other trials have provided anecdotal evidence, but these have been limited and many questioned the validity of the technique,” explained Dr. Raine-Fenning. The research team is considering a follow up study. While the scratching technique does increase the chances of live birth and clinical pregnancy, the researchers to warn that it is a considerably painful procedure and still in trial stage.

Source: Ultrasound in Obstetrics & Gynecology, MedicalNewsToday


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