BPA again – threatening fertility in unborn females


Another study is out showing the bisphenol-A or BPA, an omnipresent chemical, when exposed to a pregnant woman may damage the reproductive ability of her unborn daughter. The study is published in Environmental Health Perspectives.

Research was conducted on mice and showed that mice exposed to BPA during fetal or perinatal development had female offspring with impaired fertility. The levels they were exposed to were lower than or equal to that the average person encounters every day.

“Mice exposed to BPA in the womb and during nursing subsequently had fewer successful pregnancies and delivered fewer pups over the course of the study,” reported Ana Soto, MD, co-senior author of the study from Tufts University School of Medicine (TUSM) and a member of the Sackler School of Graduate Biomedical Sciences.

“The finding is important because standard tests of reproductive toxicology currently consist of assessing the success of a first pregnancy in young animals. If subsequent pregnancies are not examined, relevant effects may be missed,” said co-senior author Beverly Rubin, PhD, TUSM. “In addition, the infertility effect of BPA was dose-specific in our study. The lowest and highest doses we tested both impaired fertility…”

“Our findings are potentially of great relevance to humans because BPA is used in the production of materials people are exposed to every day, such as polycarbonatge plastics and the resins used to coat the inside of food and beverage cans,” said co-first author Nicolas Cabaton, PhD, at USM.

Source: Tufts University, ScienceDaily


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