Success calculator for IVF from frozen eggs


For the first time, researchers have codified age-specific probabilities of live birth after in vitro fertilization (IVF) using frozen eggs. A team of researchers from New York Medical college and the University of California Davis conducted a meta-analysis of oocyte cryopreservation cycles using individualized patient data to report the probability of live-birth from IVF cycles.

The study was published in the online May issue of the American Society for Reproductive Medicine’s journal Fertility and Sterility.

Using the largest database of implantation outcomes

Compared to other techniques, egg freezing is a relatively new development. It enables women to preserve their fertility for medical or elective reasons. Prior to this new predictor, women who were undergoing oocyte cryopreservation were unable to predict their chances of a live birth once the eggs were re-implanted. Kutluk Oktay, MD, New York Medical college physician/scientist, along with his research team collected raw data from 10 previously published studies on egg freezing creating the largest database on pregnancy outcomes after egg freezing. The database includes outcomes for 2,265 egg freezing cycles in 1,805 women in the US and Europe. From there, researchers were able to generate norms which can be sued to determine egg freezing success rates based on a woman’s age, the number of eggs frozen and the method of egg freezing.

The ability to make a well-informed decision

“Because of this breakthrough, women and fertility doctors will now be able to use a live pregnancy rate estimator to calculate their individual chances and to make a well-informed decision about the procedure,” said Dr. Oktay. The calculator shows that the success rates decline as a woman ages, but there is a significantly sharp decline after age 36. While pregnancies do result in women as late as 44, the success rates are markedly reduced after age 42.

Source: MedicalNewsToday, Fertility and Sterility


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