Study reveals breast cancer risk to fertility drug users

poic

A controversial, new report is out showing the relationship of fertility drugs to breast cancer. Women using fertility drugs who achieve a 10-plus week pregnancy have a statistically significant increased risk of breast cancer compared to unsuccessfully treated women. Compared to untreated women, there is a comparable risk of breast cancer. For women who used fertility drugs, but did not achieve pregnancy, their risk of breast cancer was significantly reduced from untreated women.

Estrogen plays a role in breast cancer

Estrogen is known to play a role in breast cancer. Ovulation-stimulating fertility drugs temporarily increase estrogen levels. “Our data suggest that exposure to a stimulated pregnancy is enough to undo the reduction in risk associated with a history of exposure to ovulation-stimulating drugs,” the authors wrote in Oxford Journal. They state that the exposure to the fertility drugs may raise risk by modifying breast tissue.

The study results are contradictory

In an accompanying editorial, Louise Brinton, PhD, Division of Cancer Epidemiology and Genetics at the National Cancer Institute, wrote that the findings are hard to understand given the conflicting results from previous tests. She stated that the reduced risk associated with drug usage may be related to the fact that clomiphene is a selective strong receptor modulator (SERM) similar to tamoxifen which is an established chemo-preventative.

Results may relate to a narrow group of women

She also postulates that the increased risk to successfully treated women may be due to increased exposure to ovarian hormones. She points out as well that this study focused on women under the age of 50 and for those women often genetic factors contribute to their cancer. She recommends caution interpreting these results.

Source: MedicalNewsToday, Oxford Journals


 
disclaimer

The information provided on ConceivingConcepts.com is designed to support, not replace, the relationship that exists between a patient/site visitor and his/her health professional. This information is solely for informational and educational purposes. The publication of this information does not constitute the practice of medicine, and this information does not replace the advice of your physician or other health care provider. Neither the owners or employees of ConceivingConcepts.com nor the author(s) of site content take responsibility for any possible consequences from any treatment, procedure, exercise, dietary modification, action or application of medication which results from reading this site. Always speak with your primary health care provider before engaging in any form of self treatment. See our Legal Statement for more details.

Fertility Clinics Directory

Find a Fertility Clinic

If you or a loved one is suffering from infertility and needs help conceiving then we are here to offer help in any way we can. We have over 450 Fertility Clinics listed on our Directory. Click here to search for a Fertility Clinic that is right for you.

babymaker