Liver let live

post meno

There are a lot of organs and glands that factor into healthy fertility. Is the liver one of them? Apparently so.

According to a study published in Cell Metabolism, there is research that shows estrogen receptors in the liver are critical for maintaining fertility. Also exciting and new is the idea that the receptors are under the control of amino acids, the building blocks of proteins and part of our everyday diets.

The information could be significant for studies and treatments of infertility, and also for menopause. “This is the first time it has been demonstrated how important the liver is in fertility,” said Adriana Maggi of The University of Milan in Italy. “the idea that diet may have an impact on fertility isn’t totally new of course, but this explains how diet, and especially a diet poor in protein, can have a direct influence.”

They accidentally came upon the information while studying mice. They noticed that the liver had the highest activation of estrogen receptors. Initially they thought it was a mistake, but it kept happening and they decided to explore it more.

Mice on restricted diets lost their ability to reproduce, their uteri would not prepare. Once a healthy protein diet was reintroduced, reproductive cycles got back on track. Carbs and fats had no effect. This may also explain why anorexics are infertile.

And it provides new information for post-menopausal women who suffer from increased risk of metabolic and inflammatory disease. These can be explained by a lack of estrogen action in the liver.

Source: Cell Press, ScienceDaily


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