Coffee impacts IVF


Coffee consumption may be hurting your success with IVF. Researchers have found that women who drink five or more cups of coffee a day reduce their change of success with IVF treatment.

Same effects as smoking

The Danish investigators described the impact as “comparable to the detrimental effect of smoking.” Results of the study showed that the consumption of five plus cups a day severely reduced the clinical pregnancy rate by 50% and the live birth rate by 40%. “Although we were not surprised that coffee consumption appears to affect pregnancy rates in IVF, we were surprised at the magnitude of the effect,” said Dr. Ulrik Schioler Kesmodel from the Fertility Clinic of Aarhus University Hospital in Denmark.

Prior studies have had conflicting results. Some found an increased instance of spontaneous abortion but others did not. A Cochrane review in 2009 showed there was a lack of evidence on either side of the argument to make a conclusive determination.

Causal link not proved; association is compelling

This latest study is different because it used a large public IVF clinic for its data and it had a follow up pool of almost four thousand women having IVF or ICSI as fertility treatment. Their coffee consumption information was obtained before the treatment started and reviewed at the beginning of each new cycle. The analysis controlled for things like age, smoking habits, alcohol consumption, cause of infertility, BMI, ovarian stimulation and number of embryos retrieved.

Less than five cups has no effect

There was no effect noted for women who drank less than five cups of coffee a day. Researchers say that while the study does not prove a causal link, there is enough evidence to suggest doctors recommend patients keep to less than five cups a day.

Source: Fertility and Sterility, MedicalNewsToday


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