Baby born from cryopreserved ovarian tissue

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Another highly anticipated birth of a baby created from cryopreserved ovarian tissue has occurred. For the first time in German, a woman gave birth to the baby after removal and preservation of ovarian tissue. The woman was undergoing chemo- and radiotherapies and the procedure was necessary to give her the best chance at preserving her fertility.

Infertility is a terrible side effect of radiation and chemotherapy. The majority of young women who need radio- or chemotherapy for treatment of tumor or other condition express very real concerns about their future fertility. The retransplantation of frozen or cryopreserved ovarian tissue is an experimental and new technique for the restoration of fertility. So far, there have been fifteen live births from this procedure which is still considered experimental and risky.

This particular woman was diagnosed with Hodgkin’s lymphoma in 2003. She was 25 years old at the time. At that time she was treated with chemotherapy and subsequently with radiation. In 2005 the disease recurred and more treatment was required to save her life. In order to protect her fertility, doctors removed ovarian tissue via laparoscopy and cryopreserved the tissue. She was then treated with high dose chemotherapy. She was free of the disease for five years when she decided it was time to try for a baby.

The preserved ovarian tissue was transplanted into her body in 2010. After hormone treatment to stimulate follicular maturation and ovulation, she was able to conceive by natural means. In October of 2011 she delivered a healthy baby via Cesarean section.

Source: MedicalNewsToday, Deutsches Aerzteblatt International


 
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