Long Life and the Higher Order Primate Hormone

Are you missing a hormone you should have? Did you realize that your adrenal gland production of a hormone called DHEA is about 10% the level at 70 as it was at 30, and in fact it declines steadily during that age range for most women. You weren't thinking about muscling up, you were thinking about being trim.  But why would we need Dihydroepiandosterone (DHEA) Figuring that supplements could help, what should you take? The experts keep saying that women loose DHEA production as they age. This is one of those so called pleiotrophic hormones...I like to think of it as a "mommy" type of hormone...mommies are all things to all people, and these hormones are maybe not 'all' things, but lots of things to lots of cells and lots of cell functions. Anyway, the point is that the DHEA hormone has been lined to age related conditions like osteoporisis, immune weakening, cardiovascular disease, diabetes, depression, and perhaps cognitive function as well. Most animals apparently, according to Drs Daneshmand and DeCherney go through drops in their DHEA the way women do (what, do these pets of progress just not live long enough), and not only that but it's a higher order molecule: only humans and high order primates secrete this stuff from their adrenal gland in significant amounts. Although elevated in many common conditions like PCOS, and responsible for some of the male hormone type side effects seen in PCOS,  it is not technically a male hormone. It cannot bind to the male (androgen) hormone receptors, but has to be converted to Androstenedione, which then has to be converted to testosterone, which in turn would have to be converted to Dihydrotestosterone to then bind to our skin and cause pimples or chin hair or bind to our muscles to pump them up. The ovary somehow pays attention to the adrenal gland, and visa versa. So when women transition into menopause, their adrenal gland does the pause as well, and begins to dip in this intriguing high order primate hormone. Physicians term this the adrenopause. So some of your fatigue, your lack of resistance, and your lack of energy, may in fact be due to that higher order primate hormone drop. And it may very well be that the secrete of living well, and living long could be tied to the drop in DHEA that you experience. Get with  your gyno, may be time to test. But once you test deficient it's not clear how much DHEAS you would need nor where you would get it as it is a hormone that would have to be compounded for you to get.


 
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