Clomid and Infertility treatment


Clomid, Serophene or clomiphene citrate (generic) is a medication used for infertility treatment. Often, it is used to induce ovulation in women who do not develop and release an egg on their own. Clomid is also frequently used to stimulate extra follicles to develop in ovaries that ovulate without additional medication. The aim is to increase the number of eggs released to increase the chance for pregnancy.

How does it work?

Clomid works as an “anti-estrogen” that tricks the brain into thinking that estrogen levels in the body are low. The drug blocks estrogen receptors in the brain from sensing estrogens in the body. So the brain thinks there isn’t a healthy level of estrogen and creates more. When the pituitary gland receives the message, it starts to create additional follicle stimulating hormone (FSH). FSH stimulates development of mature follicles in the ovaries which release additional eggs.

When does ovulation occur?

Ovulation will likely occur 7-10 days after beginning to take the Clomid pills. This will vary by woman and by whether or not she ovulates on her own. The range is actually from 2 days to three weeks.

When should intercourse take place?

Naturally, timing intercourse is key to fertilization. Unfortunately with Clomid there is no reliable ovulation calculator. Still, it doesn’t hurt to use a standard ovulation predictor kit available at any drugstore. The OPKs will measure the amount of LH in her urine which indicates that ovulation is about to occur, usually within 35 hours. Use the kit once daily and when the LH levels are detected have sex that day and/or the next day. Since healthy sperm live in the reproductive tract of a woman for three to five days, having sex every other day should ensure best results.

Source: Advanced Fertility Center of Chicago


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